About Us

Jamie Jae Eun Kim has founded 1ST Biotherapeutics, Inc. in 2016 and has been served as CEO since then, bringing a wealth of scientific leadership and business expertise. She has been engaged in all aspects of drug discovery and development as well as business development, with a particular focus on cancers, metabolic diseases and orphan diseases. Jamie has deep experience brokering R&D strategies and portfolio management in pharma R&D, with a track record of over 50 successful R&D alliances among biotech, academia, clinical research units and industry throughout her career.

Previously, Jamie was Director of the Biotherapeutics Research Center at Handok, where she was responsible for several development programs in oncology and rare diseases and for research alliance and investment. She was an Associate Director at Green Cross Corp. (Now GC Pharma), where she has newly established a discovery team in oncology and rare diseases, and, prior to that, she was a Collaboration Project Leader at Sanofi, leading collaborative research effort in oncology. Jamie spent her early career doing metabolic and oncology research leading discovery projects as a Senior Scientist at Wyeth in Pearl River, NY. She is a current member of the Global Pharma Key Opinion Leader (GPKOL) consultants and a former member of the Korea Drug Development Fund (KDDF) investment committee.

Jamie has a bachelor’s in bioengineering and master’s degree in biological science from KAIST (Korea Advanced Institute of Science and Technology). she graduated with a Ph.D. in cell and structural biology from the University of Illinois at Urbana Champaign, USA.

Jinhwa Lee has an accomplished career in drug discovery spanning academia and industry. He has helped identify and advance novel anti-bacterials, anti-virals, anti-coagulants, and therapies for metabolic syndrome, CNS disorders, and cancer. To date, he has authored 57 scientific papers and has been awarded 37 international and domestic patents.

Prior to joining 1ST Biotherapeutics, Jinhwa served as Director of the New Drug Research Center and acting Director of the Biotherapeutics Research Center at Handok. He was served as Director of the Late Discovery Program at Institut Pasteur Korea (IP-K) and prior to that, as Head of Medicinal Chemistry group at Green Cross Corporation (now, GCPharma), leading many of drug discovery/development programs and their advancement into preclinical/clinicals stages in oncology, metabolic diseases, and infectious diseases. Jinhwa was Senior Investigator at GlaxoSmithKline in Collegeville, PA, where he also earned a five -year service appreciation award.

Jinhwa has a bachelor’s and master’s degree from Seoul National University. He achieved a Ph.D. in chemistry from the University of Alabama and completed his postdoctoral research at Harvard University.

Changwon brings more than 20 years of corporate finance, business strategy, and IR experience in a diverse career and has recently led a strategic planning in the pharmaceutical industry.

Changwon was in charge of strategic planning and investment at CJ Holdings and KT Group, followed by marketing and business development at Samsung Electronics, Green Cross Well-being, Ahn-Gook Pharmaceutical, and Global Sae-a Co in charge of strategic planning and M&A.

Changwon holds B.A from Korea University and an MBA from KDI School of public policy and management.

Dr. de la Calle joined 1ST Biotherapeutics as its Chief Business Officer, while stationed in San Diego, California he will be instrumental in international partnering and corporate strategy. Most recently he was the Chief Business Officer at Eutilex where he negotiated the license of EU101, the preclinical anti-4-1BB mAb for China to Zhejiang Huahai Pharmaceutical Ltd., receiving over $31M upfront in-licensing and equity investment. He was material in developing Eutilex from a startup to a substantial publicly listed company through an IPO that yielded over $303M in immediate market cap with a high of $836M.

Before, he was working for the South Korean government supporting Korean pharmaceutical companies for success in the USA and Europe. Earlier, as head of business development at Innate Pharma, S.A. (France), he was involved in deals that lifted the company’s successful IPO to one of the largest in the Eurozone. He was Director of business development at Micromet AG (now Amgen after $1.2B acquisition) where he initiated the licensing of the scFv IP, essential for the BiTE (e.g., Blinatumomab).

Dr. de la Calle received his M.S. in physics from the Free University of Berlin. His Ph.D. was awarded from the Free University of Berlin in biochemistry after having performed his research at the Dana-Farber Cancer Institute and Harvard Medical School. He conducted his postdoctoral and business studies at MIT.

Young-Joo has experienced more than 30 years in the pharmaceutical industry, dedicating 25 years, particularly to the clinical trial field. She was responsible for advancing small molecules and biological medicines in all phases of clinical trials for both domestic and global studies. Young-Joo held roles with responsibilities not only for clinical operations but also for developing key strategies and designs across multiple early- and late-stage clinical programs.

Prior to joining 1ST Biotherapeutics, Young-Joo served as a Director of the Medical Division at JW Pharmaceutical. She was a Director of Clinical Research Division at Handok and prior to that, Head of Clinical Team at Green Cross Corp. (Now GC Pharma), responsible for leading various clinical trial programs for drugs in the therapeutic areas of anti-cancer, anti-diabetic, vaccines, cardiovascular, and CNS disorders.

Young-Joo has a bachelor’s degree in Pharmacy from Ewha Women’s University and a masters’ degree in Clinical Pharmacy from Sookmyung Women’s University and holds an M.B.A. from Ewha Women’s University.

Yong-Jun joined 1ST Biotherapeutics as a Senior Director in October 2021, bringing considerable experience in managing a drug discovery laboratory with emphasis on the early phase of drug discovery specifically, target ID/validation, in vitro/cell-based assay development, HTS/HCS, and hit-to-lead processes, and extensive knowledge in developing cell-based assay and disease model validation with cell line, IPSC derived cell line as well as biopsies from the patient. To date, he has published 28 peer-reviewed scientific papers and has been awarded several international and domestic research grants.

Most recently, Yong-Jun was responsible for early drug discovery using patient-based IPSC-derived disease models and developing personalized medicine at the Luxembourg Institute of Health, Luxembourg. Prior to that, he was responsible for early drug discovery using patient-based IPSC-derived disease models at Ksilink in Strasbourg, France. Yong-Jun has also worked in the development of personalized medicine for cancer patients, at Samsung Medical Center and has 11 years of experience in high-content screening using a Genome-wide siRNA library and chemical library in translational research at Pasteur Institutes Korea.

Yong-Jun holds a Ph.D. in Functional Genomics from the University of Yonsei in South Korea.

Soon Myung Paik is a leading pathologist and Professor at Yonsei University College of Medicine, where he heads the Severance Biomedical Science Institute, the Yonsei Genome Center, and the Yonsei Institute for Personalized Cancer Therapy.

Prof. Paik has co-authored more than 120 peer-reviewed scientific articles, evaluating current protocol and therapies for breast and bowel cancers and the role of hormones and genes in driving tumor biology. In 2017, he was awarded the HOAM Prize in medicine and the Presidential Medal (South Korea).

Phil Hyu Lee is a practicing neurologist and Professor at Yonsei University’s Department of Neurology and Severance Biomedical Science Institute. He is an expert on Parkinson’s disease and has been recognized as a top Young Investigator by the Korean Neurological Association and the Korean Movement Disorders Society.

Prof. Lee is first or corresponding author on more than 100 peer-reviewed papers and serves on the editorial board of the Journal of Clinical Neurology.

Ae Nim Pae heads the Convergence Research Center for Diagnosis, Treatment and Care System of Dementia (DTC) at the Korea Institute of Science and Technology (KIST). She oversees both basic research and drug discovery for Alzheimer’s disease and dementia; conditions that are becoming and more and more prevalent with the aging of developed nations, but that still lack effective treatments.

Prior to joining the Convergence Research Center in 2012, Dr. Pae was the Head of the KIST Center for Neuro-Medicine. She is widely published in top journals and has received a Ministry of Science and ICT award, a Presidential Award (Korea), and a Prime Minister Award (Korea) for her scientific achievement.